Maeno Ryotaku (Kataoka Ainosuke) is a doctor of Buzen Province, Nakatsu domain. Aspiring to learn Western knowledge, he comes across a Dutch-language translation of the German medical text Anatomische Tabellen while studying in Nagasaki. After returning from Nagasaki, Maeno is invited by a doctor friend Sugita Genpaku (Niiro Shinya) of Wakasa Province, Obama domain to observe an autopsy.